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life extension same 200 mg 30 tablets overall wellness (Boswellia serrata Extract [resin]) 100SAMe occurs naturally in your body, and it is a major methyl donor in the synthesis of hormones, nucleic acids, proteins, phospholipids, and more. The leves may decrease due to sickness and age. SAMe (S adenosyl methionine) is an amino acid derivative used by your body in three important pathways: Methylation (contributing methyl groups to activate certain molecules) Synthesis of polyamines (for cell growth, gene expression, neuronal regeneration,